Expression of Th1/2/17 Cytokines in CML with or without Pulmonary Bacterial and Fungal Coinfection
Table 2
Comparison of cytokine expression between uninfected patients receiving TKI treatment and non-TKI treated patients.
Parameters (pg/ml)
TKI treatment (n = 74)
No TKI treatment (n = 98)
IL-4
2.86 (1.77–4.05)
2.08 (1.26–2.79)
0.5500
IL-5
1.79 (1.08–2.56)
1.60 (1.01–2.30)
0.8370
IL-6
4.82 (2.54–8.54)
4.76 (2.54–7.25)
0.7110
IL-8
6.03 (3.37–11.67)
5.11 (2.85–8.27)
0.8740
IL-10
3.30 (2.22–4.73)
2.95 (1.92–4.05)
0.1720
IL-12p70
4.02 (2.45–4.78)
3.81 (2.90–4.86)
0.0510
IL-1β
1.76 (1.04–2.46)
1.64 (1.04–2.24)
0.7470
IL-2
2.81 (1.51–4.09)
2.48 (1.58–3.62)
0.2150
IFN-γ
2.03 (1.12–3.08)
1.88 (0.97–2.81)
0.1160
TNF-α
2.17 (1.18–2.93)
1.76 (1.03–2.74)
0.2610
TNF-β
2.07 (0.90–3.32)
1.93 (1.10–2.92)
0.1620
IL-17A
2.01 (1.39–3.02)
1.70 (1.04–2.48)
0.4360
IL-17F
2.28 (0.94–3.97)
2.23 (1.02–3.57)
0.0890
IL-22
1.19 (0.77–1.76)
1.19 (0.66–1.74)
0.1480
The difference in the expression of cytokines between TKI treatment and no treatment in noninfected patients was detected by the Mann–Whitney U test. indicates a statistical difference.
