Expression of Th1/2/17 Cytokines in CML with or without Pulmonary Bacterial and Fungal Coinfection

Table 4

Cut-off values of cytokines (AUC ≥ 0.70), CRP, PCT, and body temperature between uninfected patients and those with bacterial lung infection.

Parameters	AUC	Cut-off		Proportion of infections exceeding the cut-offvalue
CRP (mg/l)	0.80	6.18	<0.0001	64.86% (48/74)
PCT (ng/ml)	0.71	0.25	<0.0001	75.61% (31/41)
Body temperature (°C)	0.68	36.8	<0.0001	45.78% (38/83)
IL-5 (pg/ml)	0.73	2.41	<0.0001	48.31% (43/89)
IL-6 (pg/ml)	0.84	13.78	<0.0001	83.33% (45/54)
IL-8 (pg/ml)	0.82	14.35	<0.0001	67.16% (45/67)
IL-10 (pg/ml)	0.71	4.01	<0.0001	41.46% (51/123)
TNF-α (pg/ml)	0.74	3.00	<0.0001	43.33% (39/90)
IL-6, IL-8 and IL-10	—	At the same time ≥	—	93.55% (29/31)

Cut-off values of IL-5, IL-6, IL-8, IL-10, TNF-α, PCT, and CRP. Temperature are determined by the ROC curve. indicates a statistical difference.