Effect of Exosomal lncRNA MALAT1/miR-370-3p/STAT3 Positive Feedback Loop on PI3K/Akt Pathway Mediating Cisplatin Resistance in Cervical Cancer Cells

Figure 2

Effect of MALAT1 on proliferation and apoptosis of drug-resistant CC cell lines. We used the si-MALAT1 expression vector and pcDNA-MALAT1 expression vector to transfect Hela/R and C33A/R cell lines to induce ectopic expression of MALAT1. (a, b) The transfection efficiency was detected by qRT-PCR. (c–f) CCK-8 assay was used to detect cell proliferation. (g, h) Apoptosis was detected by flow cytometry. , , . All experiments were performed at least three times.

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