Research Article
Association of LAMA1 Single-Nucleotide Polymorphisms with Risk of Esophageal Squamous Cell Carcinoma among the Eastern Chinese Population
Table 1
Distribution of clinicopathological characteristics in the ESCC case and control groups.
| | | Case | Control | p value | | (n = 1043) | (n = 1143) |
| | Age (median (IQR)) | 63.00 (59.00, 68.00) | 63.00 (54.00, 70.00) | 0.257 | | Gender (%) | | | | | Female | 285 (27.3) | 315 (27.6) | 0.941 | | Male | 758 (72.7) | 828 (72.4) | | | Smoke status (%) | | | | | No | 589 (56.5) | 803 (70.3) | <0.001 | | Former/current | 454 (43.5) | 340 (29.7) | | | Alcohol consumption (%) | | | | | No | 714 (68.5) | 957 (83.7) | <0.001 | | Former/current | 329 (31.5) | 186 (16.3) | | | BMI (median (IQR)) | 22.27 (20.20, 24.35) | 23.88 (21.89, 25.88) | <0.001 | | Chronic disease (%) | | | | | No | 797 (76.4) | 604 (52.8) | <0.001 | | Yes | 246 (23.6) | 539 (47.2) | | | Hypertension (%) | 234 (22.4) | 416 (36.4) | | | Diabetes (%) | 31 (3.0) | 216 (18.9) | | | Cardiovascular disease (%) | 0 (0.0) | 59 (5.2) | | | pT stage (%) | | | | | Tis | 1 (0.1) | | | | T1a | 33 (3.2) | | | | T1b | 112 (10.7) | | | | T2 | 382 (36.6) | | | | T3 | 513 (49.2) | | | | T4 | 2 (0.2) | | | | pN stage (%) | | | | | N0 | 775 (74.3) | | | | N1 | 201 (19.3) | | | | N2 | 45 (4.3) | | | | N3 | 22 (2.1) | | | | Differentiation (%) | | | | | High | 368 (35.3) | | | | Moderate | 537 (51.5) | | | | Low | 138 (13.2) | | |
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Data are no. (%) or mean (SD) or median (IQR); BMI: body mass index; pT stage: pathological T stage; pN stage: pathological N stage.
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