Correlation between Macrophage Polarization and PD-L1-Related Tumor Microenvironmental Alteration and Metastasis in Pancreatic Ductal Adenocarcinoma

Table 4

Relationship between CD86, CD163, and clinicopathological parameters in 42 primary tumors of PDAC.

Clinicopathological parameters	CD86		value^∗	CD163		value^∗
	High	Low		High	Low
Gender			0.217			0.064
Male	9	13		8	14
Female	12	8		13	7
Maximum diameter of tumor (cm)			0.739			0.739
≤4	15	15		6	7
>4	7	6		15	14
Grade			0.123			0.355
High/moderate differentiation	8	13		9	12
Poor differentiation	13	8		12	9
Vein invasion			1.000			0.525
Yes	13	13		12	14
No	8	8		9	7
Perineural invasion			1.000			1.000
Yes	21	20		21	20
No	0	1		0	1
TNM stage			0.204			0.204
I-II	11	15		15	11
III-IV	10	6		6	10
Elevated serum CA199			0.599			1.000
Yes	18	20		19	19
No	3	1		2	2
Elevated serum CA125			0.513			0.513
Yes	6	8		8	6
No	15	13		13	15

^∗Chi-square test and Fisher’s exact test.