Correlation between Macrophage Polarization and PD-L1-Related Tumor Microenvironmental Alteration and Metastasis in Pancreatic Ductal Adenocarcinoma

Table 6

Relationship between PD-L1 and clinicopathological parameters in 42 primary tumors of PDAC.

Clinicopathological parameters	PD-L1		value^∗
	Positive	Negative
Gender			0.845
Male	6	16
Female	6	14
Maximum diameter of tumor (cm)			0.874
≤4	9	20
>4	3	10
Grade			0.063
High/moderate differentiation	3	17
Poor differentiation	9	13
Vein invasion			1.000
Yes	7	19
No	5	11
Perineural invasion			1.000
Yes	12	29
No	0	1
TNM stage			0.031
I-II	11	15
III-IV	1	15
Elevated serum CA199			1.000
Yes	11	27
No	1	3
Elevated serum CA125			1.000
Yes	4	10
No	8	20

Bold values indicate statistically significant correlations with values less than 0.05. ^∗Chi-square test and Fisher’s exact test.