Research Article
Efficacy of Recombinant Human Endostatin plus Neoadjuvant Chemotherapy for Osteosarcoma and Its Influence on Serum VEGF and MMP-9 Levels
| | Control group (n = 65) | Combination group (n = 76) | χ 2/t | |
| Gender (n (%)) | | | 0.0499 | 0.8231 | Male | 39 (60.0) | 47 (61.8) | | | Female | 26 (40.0) | 29 (38.2) | | | Average age (years) | 23.74 ± 2.48 | 24.05 ± 2.64 | 0.7146 | 0.4760 | BMI (kg/m2) | 20.97 ± 1.79 | 21.16 ± 1.94 | 0.6006 | 0.5491 | Tumor location | | | 0.8834 | 0.8294 | Ulna | 12 (18.5) | 16 (21.1) | | | Perone | 17 (26.2) | 15 (19.7) | | | Tibia | 20 (30.7) | 26 (34.2) | | | Femur | 16 (24.6) | 19 (25.0) | | | Pathological type | | | 1.3992 | 0.4970 | Osteoblast | 41 (63.1) | 55 (72.4) | | | Chondroblast | 14 (21.5) | 12 (15.8) | | | Fibroblast | 10 (15.4) | 9 (11.8) | | | Enneking stage | | | 0.7495 | 0.6875 | IIA | 10 (15.4) | 8 (10.5) | | | IIB | 48 (73.8) | 59 (77.6) | | | III | 7 (10.8) | 9 (11.9) | | |
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