Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma

<div>Combined treatment of PB and PF inhibited the proliferation and colony formation of TSCC cells. (a) Results of the Edu assay demonstrated the inhibited proliferation of Cal27 and Cal27/CDDP cells following the treatment with PB and/or PF. (b-c) Histogram of Edu fluorescence in Cal27 and Cal27/CDDP cells. (d) Colony formation of Cal27 and Cal27/CDDP cells following the treatment with PB and/or PF. (e-f) Histogram of numbers of colonies of Cal27 and Cal27/CDDP cells. 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Journal of Oncology

fig2

Figure 2

Figure 2: Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma 

Figure 2 | Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma 