Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma

<div>Combined PB and PF induced S phase arrest of TSCC cells. (a) A representative cell cycle in Cal27 and Cal27/CDDP cells following the treatment with PB and/or PF. (b-c) A histogram of cell cycle distribution in Cal27 and Cal27/CDDP cells. PB, plumbagin; PF, cisplatin plus 5-fluorouracil; and TSCC, tongue squamous cell carcinoma.</div>

Journal of Oncology

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Figure 4: Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma 

Figure 4 | Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma 