A Novel Method for Dynamically Assessing the Prognosis of Patients with pT1 Gastric Cancer: A Large Population-Based Dynamic Prognostic Analysis

Table 2

Univariate Cox hazards regression analyses of independent prognosis factors for the prediction nomogram.

Characteristics	Univariate analysis
	HR	95% CI	value
Sex			0.174
Male	Ref
Female	0.860	0.692–1.069	0.174
Age			<0.001
≤40	Ref
>40 and ≤50	1.314	0.362–4.776	0.678
>50 and ≤60	1.731	0.525–5.705	0.367
>60 and ≤70	3.503	1.108–11.079	0.033
>70	6.060	1.938–18.953	0.002
Size			<0.001
≤1 cm	Ref
>1 cm and ≤2 cm	1.237	0.872–1.754	0.233
>2 cm and ≤3 cm	1.780	1.247–2.542	0.001
>3 cm and ≤4 cm	1.941	1.325–2.842	<0.001
>4 cm	2.461	1.693–3.577	0.001
Grade			0.299
Well differentiated	Ref
Moderately differentiated	1.470	0.983–2.197	0.060
Poorly differentiated	1.306	0.887–1.923	0.176
Undifferentiated	1.248	0.519–2.999	0.620
Tumor location			0.270
Upper	Ref
Middle	0.755	0.423–1.348	0.342
Lower	0.629	0.369–1.073	0.089
Overlapping	0.728	0.427–1.242	0.244
pT stage			<0.001
pT1a	Ref
pT1b	1.987	1.548–2.551	<0.001
pN stage			<0.001
pN0	Ref
pN1	2.427	1.857–3.172	<0.001
pN2	2.562	1.812–3.624	<0.001
pN3a	2.564	1.359–4.839	0.004
pN3b	5.485	2.257–13.330	<0.001
Number of retrieved LNs			<0.001
≤15	Ref
>15	0.651	0.514–0.824	<0.001
Adjuvant therapy			0.001
Yes	Ref
No/Unknown	1.521	1.175–1.968	0.001

HR, hazard rate; CI, confidence interval. Bold values indicate the significant difference with P < 0.05.