CD86 Is Associated with Immune Infiltration and Immunotherapy Signatures in AML and Promotes Its Progression

Figure 1

CD86 was associated with immunoassay sites in pan-cancers. (a) Correlation between CD86 and immunomodulators (chemokines, receptors, MHC, and immunostimulators). (b–e) Correlation between CD86 and four immune checkpoints, PDCD1, CTLA4, CD274, and LAG3. The dots represent cancer types. The Y-axis represents the Pearson correlation, while the X-axis represents –log10P. (f) Correlation between diffuse carcinoma and 28 tumor-associated immune cells calculated with the ssGSEA algorithm. The color indicates visual cues the correlation coefficient (red is positive, blue is negative). The asterisks indicate a statistically significant value calculated using Spearman correlation analysis. ().

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