Body Weight Control by a High-Carbohydrate/Low-Fat Diet Slows the Progression of Diabetic Kidney Damage in an Obese, Hypertensive, Type 2 Diabetic Rat Model

Figure 6

TGF-beta in renal tissues and its induction in vitro by TNF-alpha. (a) Gene expressions of TGF-beta, CTGF, and PAI-1 in MC/MF (white bar) and HC/LF (black bar).*$P<.05$, **$P<.01$. (b) Effects of TNF-alpha on TGF-beta mRNA expressions in vitro in cultured rat proximal tubular cells (IRPTC). *$P<.05$, **$P<.01$.

(a)

(b)