|
| Gene Symbol | Gene title | Fold change |
|
| Cellular lipid metabolic process | | CR × DIO |
| Slc27a1 | Solute carrier family 27 (fatty acid transporter) | 2.53 | up |
| Fads2 | Fatty acid desaturase 2 | 2.18 | up |
| Ces3 | Carboxylesterase 3 | 2.51 | up |
| Sult1a1 | Sulfotransferase family 1A | 2.22 | up |
| Ptges | Prostaglandin E synthase | 2.25 | up |
| Sgpp1 | Sphingosine-1-phosphate phosphatase 1 | 2.73 | down |
| Echs1 | Enoyl Coenzyme A hydratase | 2.00 | up |
| Hsd11b1 | Hydroxysteroid 11-beta dehydrogenase 1 | 3.28 | up |
| Apoc3 | Apolipoprotein C-III | 5.71 | up |
| Srebf1* | Sterol regulatory element binding transcription factor 1 | 2.98 | up |
| Aldh1a7 | Aldehyde dehydrogenase family 1 | 2.18 | up |
| Hpgd | Hydroxyprostaglandin dehydrogenase 15 (NAD) | 2.09 | down |
| Rdh11 | Retinol dehydrogenase 11 | 4.59 | up |
| Rarres2 | Retinoic acid receptor responder (tazarotene induced) 2 | 2.61 | down |
| Nsdhl* | NAD(P) dependent steroid dehydrogenase-like | 2.65 | up |
| Gpam | Glycerol-3-phosphate acyltransferase | 2.06 | up |
| Hmgcs1* | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 3.01 | down |
| Abat | 4-aminobutyrate aminotransferase | 2.88 | down |
| Sorl1 | Sortilin-related receptor | 2.77 | up |
| Pip4k2a | Phosphatidylinositol-5-phosphate 4-kinase | 2.02 | down |
| Acaca | Acetyl-Coenzyme A carboxylase alpha | 4.60 | up |
| Tm7sf2* | Transmembrane 7 superfamily member 2 | 3.69 | up |
| Sc5d* | Sterol-C5-desaturase | 2.11 | up |
| Fdft1* | Farnesyl diphosphate farnesyl transferase 1 | 2.68 | up |
| Hsd17b12* | Hydroxysteroid (17-beta) dehydrogenase 12 | 2.17 | up |
| Pcx* | Pyruvate carboxylase | 2.88 | up |
|
| Cellular carbohydrate metabolic process | | | |
| Fn3k | Fructosamine 3 kinase | 4.05 | up |
| Chst1* | Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 2.00 | up |
| Dlat | Dihydrolipoamide S-acetyltransferase | 2.59 | up |
| Pkm2 | Pyruvate kinase | 2.37 | up |
| Pmm1 | Phosphomannomutase 1 | 2.72 | up |
| Ppp1r1a | Protein phosphatase 1 | 2.61 | up |
| Pgd | Phosphogluconate dehydrogenase | 2.40 | up |
| Agl | Amylo-1 | 2.16 | up |
| Oxct1 | 3-oxoacid CoA transferase 1 | 2.17 | down |
| Pdk1 | Pyruvate dehydrogenase kinase | 3.07 | up |
| Gpd1 | Glycerol-3-phosphate dehydrogenase 1 (soluble) | 2.02 | up |
| Taldo1 | Transaldolase 1 | 2.03 | up |
|
| Glucose transport | | | |
| Sh2b2* | SH2B adaptor protein 2 | 3.26 | up |
| Slc2a4 | Solute carrier family 2 (facilitated glucose transporter) | 3.43 | up |
| Pcx* | Pyruvate carboxylase | 2.88 | up |
| Klf15 | Kruppel-like factor 15 | 2.36 | up |
|
| Immune response | | CR × DIO |
| Malt1 | Mucosa associated lymphoid tissue Lymphoma translocation gene 1 | 2.55 | down |
| Bcl6* | B-cell leukemia/lymphoma 6 | 2.90 | down |
| Clec7a* | C-type lectin domain family 7 | 2.89 | down |
| Cfb | Complement factor B | 2.53 | down |
| Cd55* | CD55 antigen | 2.25 | Down |
| Thy1 | Thymus cell antigen 1 | 2.44 | down |
|
| Biosynthesis of Steroids | | | |
| Lss | Lanosterol synthase | 2.13 | up |
| Hmgcs1* | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 3.01 | down |
| Tm7sf2* | Transmembrane 7 superfamily member 2 | 3.69 | up |
| Sc5d* | Sterol-C5-desaturase | 2.11 | up |
| Fdft1* | Farnesyl diphosphate farnesyl transferase 1 | 2.68 | up |
| Hsd17b12* | Hydroxysteroid (17-beta) dehydrogenase 12 | 2.17 | up |
| Nsdhl* | NAD(P) dependent steroid dehydrogenase-like | 2.65 | up |
| Sh2b2* | SH2B adaptor protein 2 | 3.26 | up |
|
| Stress response | | | |
| Thbs1 | Thrombospondin 1 | 2.29 | down |
| Tfpi2 | Tissue factor pathway inhibitor 2 | 4.32 | down |
| Gp1bb | Glycoprotein Ib | 2.06 | up |
| Taok3 | TAO kinase 3 | 2.21 | down |
| Sod3 | Superoxide dismutase 3 | 2.17 | down |
| Dusp10 | Dual specificity phosphatase 10 | 2.62 | down |
| Adrb3 | Adrenergic receptor | 2.09 | up |
| F2r | Coagulation factor II (thrombin) receptor | 2.22 | down |
| Ccnd1 | Cyclin D1 | 2.91 | down |
| Evl | Ena-vasodilator stimulated phosphoprotein | 2.32 | down |
| Ctsb | Cathepsin B | 2.00 | down |
| Ly86 | Lymphocyte antigen 86 | 2.65 | down |
| Fabp4 | Fatty acid binding protein 4 | 2.03 | up |
| Rad50 | RAD50 homolog (S. cerevisiae) | 2.27 | down |
| Tsc22d2 | TSC22 domain family 2 | 2.41 | down |
| Ptger3 | Prostaglandin E receptor 3 (subtype EP3) | 2.21 | up |
| Lcp1 | Lymphocyte cytosolic protein 1 | 3.06 | down |
| Pros1 | Protein S (alpha) | 2.09 | down |
| Hspa12a | Heat shock protein 12A | 2.40 | down |
| Anxa2 | Annexin A2 | 2.01 | down |
| Uhrf1 | Ubiquitin-like | 2.84 | down |
| Cdkn1a | Cyclin-dependent kinase inhibitor 1A (P21) | 2.28 | down |
| Srebf1* | Sterol regulatory element binding transcription factor 1 | 2.98 | up |
| Chst1* | Carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 2.00 | up |
| Bcl6* | B-cell leukemia/lymphoma 6 | 2.90 | down |
| Clec7a* | C-type lectin domain family 7 | 2.89 | down |
| Cd55* | CD55 antigen | 2.25 | down |
|
| Exercise unique | | | |
| Mitochondrial Transport | | EX × DIO |
| Ucp1 | Uncoupling protein | 8.94 | up |
| Ucp2 | Uncoupling protein 2 | 2.09 | down |
|
