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EOSS stage | Conceptual EOSS definition (Sharma and Kushner, 2009) [1] | Study operational definition |
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0 | No apparent obesity-related risk factors, physical symptoms, psychopathology, functional limitations, and/or impairments of well-being | No EOSS factors reported |
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1 | Presence of obesity-related subclinical risk factors, mild physical symptoms, mild psychopathology, mild functional limitations, and/or impairment of well-being | Any of the following: (i) Glucose ≥ 5.6 mmol/L (ii) Cholesterol ≥ 5.2 mmol/L (iii) Triglycerides ≥ 1.7 mmol/L (iv) HDL ≤ 1.6 mmol/L (v) LDL ≥ 3.3 mmol/L (vi) SBP ≥ 130 mmHg (vii) DBP ≥ 85 mmHg |
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2 | Presence of established obesity-related chronic disease, moderate limitations in activities of daily living, and/or well-being | Any of the following: (i) Glucose ≥ 6.9 mmol/L (ii) Diagnosed type 2 diabetes or type 2 diabetes medication (iii) Cholesterol ≥ 6.2 mmol/L (iv) Diagnosed hypercholesterolaemia (v) Triglycerides ≥ 2.2 mmol/L (vi) HDL ≤ 1.0 mmol/L (vii) LDL ≥ 4.1 mmol/L (viii) Diagnosed hyperlipidaemia or hyperlipidaemia medication (ix) SBP ≥ 140 mmHg (x) DBP ≥ 90 mmHg (xi) Diagnosed hypertension or hypertension medication (xii) Sleep apnea (xiii) Gout (xiv) Arthritis (xv) Anxiety (xvi) Atherosclerosis (xvii) Fatty liver (xviii) Congestive heart failure medication (xix) Blood thinner medication (xx) Depression |
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3 | Established end-organ damage, significant psychopathology, significant functional limitations, and/or impairment of well-being | Any of the following: (i) Angina (ii) Heart attack (iii) Heart failure (iv) Thrombosis (v) Coronary artery disease (vi) Coronary obstructive pulmonary disease (vii) Dyspnea (viii) Exercise dyspnea (ix) Coronary artery bypass surgery (x) Stroke |
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4 | Severe (potentially end-stage) disabilities from obesity-related chronic diseases, disabling psychopathology, functional limitations, and/or impairment of well-being | No data on these factors available to evaluate this stage |
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