FTO Gene Associates and Interacts with Obesity Risk, Physical Activity, Energy Intake, and Time Spent Sitting: Pilot Study in a Nigerian Population

Table 2

Anthropometric traits of overweight and control subjects stratified by FTO rs6639609 variants.

Characteristics	Overall ()	TA ()	AA ()
	TT ()
Body weight (kg)	65.03 (8.04)	66.67 (10.49)	71.82 (8.47)	0.007
BMI (kg/m^2)	24.95 (2.50)	26.10 (3.24)	27.70 (2.88)	0.006
NC (cm)	29.72 (2.63)	30.91 (3.78)	35.20 (4.39)	<0.001
WC (cm)	78.20 (7.14)	82.70 (7.46)	86.33 (8.21)	0.026
WHtR	0.481 (0.05)	0.519 (0.05)	0.532 (0.06)	0.006
WHR	0.840 (0.07)	0.883 (0.07)	0.957 (0.08)	0.002
R2D : 4D	0.9586 (0.02)	0.9742 (0.02)	0.9894 (0.04)	0.0026
L2D : 4D	0.9570 (0.02)	0.9726 (0.02)	0.9816 (0.03)	0.013
Energy intake (kcal/day)	1662.00 (377.76)	1891.67 (370.25)	2273.89 (537.91)	0.008
TSS (minutes/week)	300.13 (129.75)	465.22 (151.73)	541.94 (160.62)	0.003
TPA	1668.00 (4177–99)	625.25 (4120–40)	645.00 (2826–89.5)	<0.001
VPA	792.00 (1782–0)	297.00 (1782–0)	231.00 (1386–33)	<0.001
MPA	480.00 (1800–0)	170.00 (1760–0)	120.00 (1440–0)	<0.001
LPA	96.00 (1800–0)	0 (1680–0)	0 (1800–0)	0.066

Data are expressed as mean (SD values presented in parenthesis) except stated otherwise; ANOVA test (Bonferroni multiple comparability test) was used to compare means across genotype while Kruskal–Wallis test was used to test the difference in physical activity; BMI: body mass index, NC: neck circumference, WC: waist circumference, WHR: waist to hip ratio, WHtR: waist to height ratio, R2D : 4D: ratio of right hand second to fourth digit, and L2D : 4D: ratio of left hand second to fourth digit; TSS: time spent sitting, TPA: total physical activity, VPA: vigorous physical activity, MPA: moderate physical activity, and LPA: low physical activity; data expressed with the same superscript in the same row are not statistically different at ; data are expressed by median (range); Kruskal–Wallis test (comparability test Dunns).