Metabolomic Links between Sugar-Sweetened Beverage Intake and Obesity

Table 3

The ten metabolites that are significantly associated with both SSB intake and BMI and overrepresented in the PC/PE biosynthetic pathways.

Metabolic pathways/metabolite	SSB intake			BMI
	Beta	SE	value	Beta	SE	value
Phosphatidylcholine (PC)
1-Stearoyl-2-linoleoyl-GPC (18 : 0/18 : 2)	0.016	0.008	0.033	−2.975	1.218	1.48E − 02
1,2-Dilinoleoyl-GPC (18 : 2/18 : 2)	0.039	0.016	0.014	−2.976	0.666	9.14E − 06
1-Palmitoyl-2-stearoyl-GPC (16 : 0/18 : 0)	0.036	0.012	0.002	−2.571	0.783	1.08E − 03
1-Linoleoyl-2-linolenoyl-GPC (18 : 2/18 : 3)	0.076	0.030	0.011	−0.910	0.240	1.57E − 04
Lysophospholipid (LPL)
1-Palmitoyl-GPC (16 : 1)	0.071	0.017	4.27E − 05	−0.893	0.367	1.53E − 02
1-Palmitoyl-GPC (16 : 0)	0.020	0.009	3.03E − 02	−7.337	1.473	7.84E − 07
1-Oleoyl-GPE (18 : 1)	0.049	0.021	2.02E − 02	−1.216	0.366	9.42E − 04
1-Linoleoyl-GPE (18 : 2)	0.061	0.019	1.21E − 03	−1.356	0.368	2.44E − 04
1-Oleoyl-GPI (18 : 1)	0.053	0.025	3.28E − 02	−1.205	0.339	3.93E − 04
1-Oleoyl-GPC (18 : 1)	0.028	0.013	2.99E − 02	−4.917	0.792	8.80E − 10

All , beta, and SE values were estimated based on a linear regression model adjusted for age, sex, smoking, alcohol use, and physical activity score.