Therapeutic Effect of P-Cymene on Lipid Profile, Liver Enzyme, and Akt/Mtor Pathway in Streptozotocin-Induced Diabetes Mellitus in Wistar Rats

Figure 1

Dithizone staining of pancreatic tissues in all animal groups. The red or DTZ positive regions indicate the B-cells in islets of Langerhans. Administration of metformin or p-cymene obviously increased the B-cell mass in Met, D50, and D100 groups in a dose-dependent manner. C: control rats, D: the sham or diabetic rats, MET: diabetic rats + metformin (55 mg/kg), C25: control rats + p-cymene (25 mg/kg), C50: control rats + p-cymene (50 mg/kg), C100: control rats + p-cymene (100 mg/kg), D25: diabetic rats + p-cymene (25 mg/kg), D50: diabetic rats + p-cymene (50 mg/kg), and D100: diabetic rats + p-cymene (100 mg/kg). Magnification 400x Scale bar 100 μm.