Biochemical Predictors of New-Onset Atrial Fibrillation after Ascending Aorta Replacement Surgery in Acute Type A Aortic Dissection Patients
Table 1
Perioperative information of the 435 patients with or without POAF.
No-POAF 217 (49.9%)
POAF 218 (50.1%)
value
Preoperation
Age (y)
49 ± 11
60 ± 13
<0.001
Male, n (%)
181 (83.5%)
164 (75.2%)
0.035
Body mass index (kg/m2)
25.47 (23.25–28.06)
24.90 (22.86–27.35)
0.093
Hypertension, n (%)
160 (73.7%)
174 (79.8%)
0.133
Smoking history, n (%)
69 (31.8%)
57 (26.1%)
0.194
Alcohol consumption history, n (%)
54 (24.9%)
52 (23.9%)
0.802
Pericardial effusion, n (%)
169 (77.9%)
181 (83.0%)
0.176
Haemodynamic instability, n (%)
8 (3.7%)
13 (6%)
0.371
Intraoperation
Operative time (h)
6.50 (6.0–7.8)
6.60 (5.6–8.0)
0.887
CPB time (min)
191.00 (161.00–230.75)
200.00 (165.25–240.00)
0.316
DHCA time (min)
26 (19–36)
25 (19–35)
0.629
Aortic clamp time (min)
142.0 (116.00–174.75)
142.5 (114.25–178.00)
0.432
Bentall procedure, n (%)
38 (17.5%)
39 (17.9%)
1.000
Wheat’s procedure, n (%)
6 (2.8%)
7 (3.2%)
1.000
Aortic valve replacement, n (%)
44 (20.3%)
46 (21.1%)
0.906
Descending aorta stent implantation, n (%)
181 (83.4%)
179 (82.1%)
0.800
Extend arch repair, n (%)
60 (27.6%)
48 (22.0%)
0.184
Cerebral perfusion
0.141
No
61 (28.1%)
63 (28.9%)
UACP
134 (61.8%)
125 (57.3%)
BACP
11 (5.1%)
7 (3.2%)
RCP
11 (5.1%)
23 (10.6%)
LTN (°C)
22.95 (22.00–25.85)
22.70 (21.80–23.88)
0.309
RBC transfusion (U)
9.0 (5.5–12.5)
10.5 (7.5–15.0)
0.002
Postoperation
Hemoglobin (g/L)
96 (84–107)
93 (85–105)
0.368
C-reactive protein (mg/L)
181.0 (145.8–218.1)
178.9 (140.9–218.1)
0.378
Apolipoprotein A (g/L)
0.62 (0.54–0.70)
0.61 (0.54–0.68)
0.191
Apolipoprotein B (g/L)
0.40 (0.32–0.51)
0.37 (0.30–0.45)
0.008
Adenosine deaminase (U/L)
7.2 (6.0–9.0)
8.0 (7.1–10.2)
<0.001
Leucine aminopeptidase (U/L)
40.50 (34.80–46.75)
40.00 (34.45–47.65)
0.877
Lactic dehydrogenase (U/L)
461 (370–651)
493 (382–798)
0.111
Aspartate aminotransferase (U/L)
48 (30.5–103.2)
54 (32.8–142.6)
0.159
Alanine aminotransferase (U/L)
21.6 (14.5–39.8)
21.5 (14.6–53.5)
0.47
Albumin globulin ratio
1.97 (1.78–2.24)
1.99 (1.78–2.26)
0.64
Cholesterol (mmol/L)
2.69 (2.33–3.05)
2.44 (2.14–2.9)
0.001
HDL (mmol/L)
0.69 (0.50–0.89)
0.68 (0.5–0.85)
0.624
LDL (mmol/L)
1.04 (0.81–1.35)
0.93 (0.69–1.16)
0.001
Cholinesterase (KU/L)
4.5 (3.9–5)
4.1 (3.6–4.7)
0.002
Triglyceride (mmol/L)
1.05 (0.79–1.43)
0.94 (0.68–1.4)
0.049
Total bile acid (umol/L)
3.4 (1.8–6.7)
4.1 (2.5–7.9)
0.012
Glucose (mmol/L)
6.68 (6.08–7.55)
7.17 (6.31–8.63)
0.001
Uric acid (umol/L)
295 (225–383)
309 (235–413)
0.291
Urea nitrogen (mmol/L)
9.8 (7.3–13.2)
11.6 (8.9–14.7)
0.002
Creatinine (umol/L)
95 (70–164)
110 (73–188)
0.134
Calcium (mmol/L)
2.12 (2.04–2.22)
2.12 (2.04–2.23)
0.95
Sodium (mmol/L)
146.8 (144–149.4)
147.2 (143.8–149.8)
0.447
Chlorine (mmol/L)
109 (105.9–111.8)
108.9 (106.4–112)
0.917
Phosphorus (mmol/L)
0.85 (0.68–1.07)
0.86 (0.71–1.12)
0.24
Potassium (mmol/L)
4.28 (4.11–4.47)
4.35 (4.18–4.52)
0.015
CBP time, cardiopulmonary bypass time; DHCA time, deep hypothermia circulatory arrest time; UACP, unilateral anterograde cerebral perfusion; BACP, bilateral anterograde cerebral perfusion; RCP, retrograde cerebral perfusion; LTN, lowest temperature of nasopharyngeal; RBC transfusion, red blood cell transfusion; HDL, high-density lipoprotein; LDL, low-density lipoprotein. The bold values in the p-value column are less than 0.05, which indicates statistical significance.
