Research Article

Prevalence and Predictive Factors of Early Degeneration of Bioprosthetic Mitral Valves: A Single-Center Cohort Study

Table 2

Perioperative characteristics and surgical complications of the study population and their comparison between patients with and without bioprosthetic mitral valve early degeneration.

CharacteristicsTotal (n = 177)Normal (n = 138)Degeneration (n = 39) value

Type of surgery0.70
Valve replacement69 (39.0)56 (40.6)13 (33.3)
Valve replacement + CABG45 (25.4)33 (23.69)12 (30.8)
Valve + CABG + other18 (10.2)15 (10.9)3 (7.7)
Valve + other45 (25.4)34 (24.6)11 (28.2)

Manufacturer of the valve, n (%)0.63
Perimount117 (66.1)91 (65.9)26 (66.7)
Hancock I13 (7.3)11 (8.0)2 (5.1)
Hancock II29 (16.4)23 (16.7)6 (15.4)
Biocor12 (6.8)9 (6.5)3 (7.7)
Epic3 (1.7)1 (0.7)2 (5.1)
Magna2 (1.1)2 (1.4)0 (0)
St. Jude1 (0.6)1 (0.7)0 (0)

Size of the valve, n (%)0.14
241 (0.6)01 (2.6)
254 (1.7)4 (2.2)0 (0)
2789 (50.3)64 (46.4)25 (64.1)
2961 (34.5)50 (36.2)11 (28.2)
3120 (11.3)18 (13.0)2 (5.1)
332 (1.1)2 (1.4)0 (0)

In hospital anticoagulant, n (%)171 (96.6)133 (96.4)38 (97.4)0.75
Aspirin, n (%)152 (85.9)121 (87.7)31 (79.5)0.20
Total ICU stay, hour67.0 [26.3, 109.0]69.0 [27.8, 110.7]68.5 [30.1, 135.5]0.72
Total ventilation duration, hour13.0 [10.5, 18.0]13.3 [10.5, 18.9]16.3 [11.9, 26.3]0.10
Cross clamp time, minutes72.5 ± 32.772.3 ± 34.173.2 ± 27.70.87
ICU readmission, n (%)12 (6.8)9 (6.5)3 (7.7)0.80
Reintubation, n (%)15 (8.5)11 (8.0)4 (10.3)0.65
Packed cell transfusion, n (%)105 (59.3)79 (57.2)26 (66.7)0.29

In-hospital complications
Atrial fibrillation, n (%)71 (40.1)56 (40.6)15 (38.5)0.81
Pericardial effusion, n (%)12 (6.8)9 (6.5)3 (7.7)0.80
Pleural effusion, n (%)24 (13.6)16 (11.6)8 (20.5)0.15
Cardiac arrest, n (%)2 (1.1)2 (1.4)0 (0)0.99
Tamponade, n (%)2 (1.1)0 (0)2 (5.1)0.05
Pneumonia, n (%)2 (1.1)2 (1.4)0 (0)0.99
Prolonged ventilation, n (%)26 (14.7)18 (13.0)8 (20.5)0.25
Hemodialysis, n (%)1 (0.6)0 (0)1 (2.6)0.22
Reoperation due to valvular dysfunction, n (%)1 (0.6)0 (0)1 (2.6)0.22
Death, n (%)2 (1.1)1 (0.7)1 (2.6)0.40

was considered statistically significant. CABG: coronary artery bypass graft; ICU: intensive care unit.