Research Article

Left Ventricular Recovery after Transapical Transcatheter Aortic Valve Implantation Compared with Conventional Aortic Valve Replacement in Patients with Aortic Regurgitation and Reduced Ejection Fraction

Table 3

The effect of surgical strategy (TA-TAVI of C-AVR) on LVEF, LVEDD, and NYHA class using GEE models.

VariablesCrudeAdjusted
β (95% CI) valueβ (95% CI) value

LVEF
Surgical strategya0.002 (0.000 to 0.003)0.0380.002 (0.000 to 0.003)0.046

LVEDD
Surgical strategyb0.326 (0.182 to 0.470)<0.0010.330 (0.185 to 0.474)<0.001

NYHA class
Surgical strategyc0.468 (−0.124 to 1.060)0.1200.381 (−0.349 to 1.111)0.306

TA-TAVI, transapical transcatheter aortic valve implantation; C-AVR, conventional aortic valve replacement; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic dimension; NYHA, New York Heart Association; GEE, generalized estimating equations; CI, confidence interval. aBaseline covariates in the final adjusted GEE model: age, sex, body mass index, smoking history, diabetes, hypertension, peripheral vascular disease, NYHA class, atrial fibrillation, renal insufficiency, dialysis, cancer history, stroke history, coronary artery disease, prior myocardial infarction, liver dysfunction, prior cardiac surgery, LVEDD, bicuspid aortic valve, and additive EuroScore. bBaseline covariates in the final adjusted GEE model: age, sex, body mass index, smoking history, diabetes, hypertension, peripheral vascular disease, NYHA class, atrial fibrillation, renal insufficiency, dialysis, cancer history, stroke history, coronary artery disease, prior myocardial infarction, liver dysfunction, prior cardiac surgery, LVEF, bicuspid aortic valve, and additive Euroscore. cBaseline covariates in the final adjusted GEE model: age, sex, body mass index, smoking history, diabetes, hypertension, peripheral vascular disease, atrial fibrillation, renal insufficiency, dialysis, cancer history, stroke history, coronary artery disease, prior myocardial infarction, liver dysfunction, prior cardiac surgery, LVEF, LVEDD, bicuspid aortic valve, and additive Euroscore.