Research Article
Single-Center, Multisurgeon Experience with a Sutureless Rapid Deployment Aortic Valve Prosthesis: A Clinical Analysis in the United States
Table 1
Preoperative characteristics of baseline and IPW-weighted populations in patients undergoing SLV vs. SAVR.
| | | Crude | Weighted characteristics after IPW | | SAVR | SLV | p value | SAVR | SLV | SMD | | N = 370 | N = 234 | | N (%) or mean (SD) | Weighted % or mean (SE) |
| | Primary procedure | | Isolated valve | 205 (55.4%) | 95 (40.6%) | <0.01 | 49.2 | 48.9 | 0.012 | | CABG + valve | 165 (44.6%) | 139 (59.4%) | | 50.80 | 51.10 | | | Patient characteristics | | Age at surgery, years | | | | | | | | Mean (SD) | 68.0 (9.7) | 71.6 (8.3) | <0.01 | 69.5 (0.52) | 70.2 (0.64) | 0.08 | | <60 | 74 (20.0) | 26 (11.1) | <0.01 | 16.4 | 15.8 | 0.015 | | 60–69 | 132 (35.7) | 68 (29.1) | | 32.7 | 32.7 | 0.002 | | 70–79 | 132 (35.7) | 102 (43.6) | | 38.7 | 39.3 | 0.012 | | >80 | 32 (8.7) | 38 (16.2) | | 12.2 | 12.2 | 0.001 | | Female (%) | 101 (27.3%) | 73 (31.2%) | 0.30 | 29.00 | 29.30 | 0.01 | | Body surface area, m2 | | | | | | | | Mean (SD) | 2.0 (0.3) | 2.0 (0.2) | 0.31 | 2 (0.02) | 2 (0.01) | 0.018 | | <1.70 | 27 (7.3%) | 24 (10.3%) | 0.40 | 8.5 | 8.3 | 0.007 | | 1.70–1.99 | 134 (36.2%) | 86 (36.8%) | | 37 | 36.8 | 0.006 | | ≥2.00 | 209 (56.5%) | 124 (53.0%) | | 54.5 | 55 | 0.009 | | Disease characteristics | | Preoperative WBC count >12,000 mm3 | 5 (1.4%) | 9 (3.8%) | 0.05 | 2 | 2.3 | 0.018 | | Prior CABG surgery | 3 (0.8%) | 3 (1.3%) | 0.57 | 0.51 | 0.56 | 0.009 | | Prior valve surgery | 13 (3.5%) | 14 (6.0%) | 0.15 | 4 | 4.4 | 0.006 | | Prior PCI | 38 (10.3%) | 47 (20.1%) | <0.01 | 14.8 | 15 | 0.006 | | Prior CVA | 16 (4.3) | 18 (7.7) | 0.08 | 4.3 | 4.1 | 0.008 | | Preoperative atrial fibrillation | 67 (18.1%) | 49 (20.9%) | 0.39 | 18.8 | 19 | 0.007 | | Comorbid disease | | | | | | | | Vascular disease | 202 (54.6%) | 114 (48.7%) | 0.16 | 51.6 | 50.3 | 0.027 | | Diabetes | 118 (31.9%) | 95 (40.6%) | 0.03 | 34.2 | 35.1 | 0.017 | | COPD | 73 (19.7%) | 50 (21.4%) | 0.63 | 20.5 | 20 | 0.011 | | Smoker | 45 (12.2%) | 22 (9.4%) | 0.29 | 11.6 | 9.6 | 0.067 | | Congestive heart failure | 138 (37.3%) | 88 (37.6%) | 0.94 | 36.5 | 36.1 | 0.007 | | History of dialysis or creatinine >1.3 mg/dL | 33 (8.9%) | 39 (16.7%) | <0.001 | 13.1 | 12 | 0.008 | | Prior myocardial infarction ≤7 days | 13 (3.5%) | 15 (6.4%) | 0.09 | 5.3 | 5.6 | 0.007 | | Three-vessel coronary disease | 72 (18.3) | 87 (32.8) | <0.01 | 14.7 | 15.2 | | | Ejection fraction (%) | | | | | | | | Mean (SD) | 57.4 (10.1) | 57.3 (9.3) | 0.96 | 57.7 (0.51) | 57.3 (0.69) | 0.037 | | <40 | 28 (7.6%) | 14 (6.0%) | 0.43 | 6.9 | 6.8 | 0.002 | | 40–49 | 20 (5.4%) | 20 (8.5%) | | 5.3 | 6.9 | 0.064 | | 50–59 | 126 (34.1%) | 81 (34.6%) | | 34.1 | 34.9 | 0.017 | | ≥60 | 196 (53.0%) | 119 (50.9%) | | 53.8 | 51.4 | 0.048 | | Priority at surgery | | | 0.11 | | | | | Urgent | 86 (23.2%) | 68 (29.1%) | | 25.4 | 25.4 | 0.001 | | Elective | 284 (76.8%) | 166 (70.9%) | | 74.6 | 74.6 | 0.001 |
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SAVR: surgical aortic valve replacement; SD: standard deviation; SMD: standardized mean difference of the mean; CABG: coronary artery bypass graft surgery; WBC: white blood cell; PCI: percutaneous coronary intervention; COPD: chronic obstructive pulmonary disease; CVA: cerebrovascular accident and stroke. values obtained from chi-squared tests and two sample t-tests. |
