Mortality and Survival after Norwood Procedure Comparison between Shunt Type in Patients with Hypoplastic Left Heart Syndrome or Its Variants: A Systematic Review and Meta-Analysis Study

Table 1

Studies’ characteristics.

Study ID	Last name, year	Study design	Database/Unit	Country	Study timeline
1	Ono et al., 2021 [11]	Retrospective cohort study	German Heart center Munich	Germany	2001–2019
2	Vitanova et al., 2019 [6]	Retrospective cohort study	German Heart center Munich	Germany	2001–2017
3	Kelly et al., 2019 [12]	Retrospective cohort study	The Royal Children’s Hospital	Australia	Era 1: 2004-2008. Era 2: 2008–2016
4	Anton-Martin et al., 2019 [13]	Retrospective cohort study	Phoenix Children’s Hospital	USA	2013–2016
5	Newburger et al., 2018 [14]	RCT	Pediatric heart network	USA and Canada	2005–2008
6	Mahle et al., 2018 [5]	RCT	Pediatric heart network	USA and Canada	2005–2008
7	Hall et al., 2017 [15]	Prospective cohort study	Vanderbilt University Medical center	USA	2007–2015
8	Buelow et al., 2018 [16]	Prospective cohort study	National Pediatric Cardiology Quality Improvement Collaborative, Children’s Hospital of Wisconsin	USA	2008–2014
9	Wilder et al., 2017 [17]	Prospective cohort study	Congenital Heart Surgeons’ Society Data center	USA	2005–2014
10	Ruotsalainena et al., 2017 [18]	Retrospective cohort study	Children’s Hospital, University of Helsinki, Helsinki, Finland	Finland	2003–2010
11	Ravishankar et al., 2016 [19]	RCT	Pediatric heart network	USA, Canada	2005–2008
12	Murthy et al., 2016 [20]	RCT	Pediatric heart network	USA, Canada	2006–2013
13	Carlo et al., 2016 [21]	Prospective cohort study	The Pediatric Heart Transplant Study (PHTS) database	USA, UK, Canada	2010–2013
14	Wilder et al., 2015 [22]	Prospective cohort study	Congenital Heart Surgeons’ Society Data center	Canada, USA	2005–2014
15	Newburger et al., 2014 [7]	RCT	Pediatric heart network	USA, Canada	2005–2008
16	Burch et al., 2014 [23]	RCT	Pediatric heart network	USA, Canada	2005–2008
17	Gist et al., 2013 [24]	Retrospective cohort study	Children’s Hospital Colorado	USA	2003–2011
18	Frommelt et al., 2013 [25]	RCT	Pediatric heart network	USA, Canada	2005–2008
19	Fischbach et al., 2012 [26]	Retrospective cohort study	German Pediatric Heart center	Germany	2002–2009
20	Tweddell et al., 2012 [27]	RCT	Pediatric heart network	USA, Canada	2005–2008
21	Tabbutt et al., 2012 [28]	RCT	Pediatric heart network	USA, Canada	2005–2008
22	Polimenakos et al., 2012 [29]	Retrospective cohort study	Advocate Hope Children’s Hospital	USA	2005–2009
23	Photiadis et al., 2012 [30]	Retrospective cohort study	German Pediatric Heart center	Germany	2002–2009
24	Ohye et al., 2012 [31]	RCT	Pediatric heart network	USA, Canada	2005–2008
25	Newburger et al., 2012 [32]	RCT	Pediatric heart network	USA, Canada	2005–2008
26	Murtuza et al., 2012 [33]	Retrospective cohort study	Birmingham Children’s Hospital	UK	2002–2010
27	Menon et al., 2012 [34]	Retrospective cohort study	Utah and the intermountain West region	USA	1995–2010
28	Ghanayem et al., 2012 [35]	RCT	Pediatric heart network	USA, Canada	2005–2008
29	Rüffer et al., 2011 [36]	Retrospective cohort study	University Heart center Hamburg	Germany	1998–2007
30	Johnson et al 2011 [37]	RCT	Pediatric heart network	USA	2005–2008
31	Fiore et al., 2011 [38]	Retrospective cohort study	Cardinal Glennon Children’s Hospital	USA	2000–2007
32	Bautista-Hernandez et al., 2011 [39]	Retrospective cohort study	Children’s Hospital Boston	USA	2000–2007
33	Ohye et al., 2010 [3]	RCT	Pediatric heart network	USA, Canada	2005–2008
34	Graham et al., 2010 [40]	Retrospective cohort study	Medical University of South Carolina	USA	2000–2005
35	Ballweg et al., 2010 [41]	Retrospective cohort study	The Children’s Hospital of Philadelphia	USA	2002–2005
36	Rüffer et al., 2009 [42]	Retrospective cohort study	University Hospital Hamburg-Eppendorf	Germany	1997–2006
37	Pruetz et al., 2009 [43]	Retrospective cohort study	Children’s Hospital Los Angeles	USA	2000–2005
38	Fabricius et al., 2009 [44]	Retrospective cohort study	Birmingham Children’s Hospital	UK	1992–2007
39	Al-Akhfash et al., 2009 [45]	Retrospective cohort study	King Abdulaziz Ccardiac center	Saudi Arabia	2001–2007
40	Scheurer et al., 2008 [46]	Retrospective cohort study	Boston Children’s Hospital	USA	2002-2003
41	Caspi et al., 2008 [47]	Retrospective cohort study	Louisiana State University and Children’s Hospital	USA	2000–2007
42	Atallah et al., 2008 [48]	Prospective cohort study	The Stollery Children’s Hospital	Canada	1996–2005
43	Silva et al., 2007 [49]	Retrospective cohort study	Hospital Beneficência Portuguesa de São Paulo	Brazil	1999–2006
44	Silva et al., 2007 [50]	Retrospective cohort study	Hospital Beneficência Portuguesa de São Paulo	Brazil	1999–2006
45	Lai et al., 2007 [51]	Retrospective cohort study	Boston Children’s Hospital	USA	2002-2003
46	Kussman et al., 2007 [52]	Retrospective cohort study	Boston Children’s Hospital	USA	2002–2004
47	Januszewska et al., 2007 [53]	Retrospective cohort study	Jagiellonian University	Poland	1995–2006
48	Graham et al., 2007 [54]	Retrospective cohort study	Medical University of South Carolina	USA	2000–2005
49	Frommelt et al., 2007 [55]	RCT	Children’s Hospital of Wisconsin	USA	2004-2005
50	Edwards et al., 2007 [56]	Retrospective cohort study	Birmingham Children’s Hospital	UK	2001–2003
51	Filippo et al., 2007 [57]	Retrospective cohort study	Children’s Hospital of Pittsburgh	USA	2000–2005
52	Ballweg et al., 2007 [58]	Retrospective cohort study	Children’s Hospital of Philadelphia	USA	2002–2005
53	Pusca et al., 2006 [59]	Retrospective cohort study	Emory University	USA	1999–2005
54	Petit et al., 2006 [60]	Retrospective cohort study	The Children’s Hospital of Philadelphia	USA	2002–2005
55	Griselli et al., 2006 [61]	Retrospective cohort study	Wales Children’s Hospital	UK	1992–2004
56	Griselli et al., 2006 [62]	Retrospective cohort study	Wales Children’s Hospital	UK	1992–2004
57	Ghanayem et al., 2006 [63]	RCT	Children’s Hospital of Wisconsin	USA	2004-2005
58	Cua et al., 2006 [64]	Retrospective cohort study	Boston Children’s Hospital	USA	2002-2003
59	Tabbutt et al., 2005 [65]	Retrospective cohort study	Children’s Hospital of Philadelphia	USA	2002–2004
60	Januszewska et al., 2005 [66]	Retrospective cohort study	Jagiellonian University	Poland	1997–2004
61	Tanoue et al., 2004 [67]	Retrospective cohort study	Fukuoka Children’s Hospital Medical center	Japan	1992–2003
62	Pizarro et al., 2004 [68]	Retrospective cohort study	Nemours Cardiac center	Poland	2000–2003
63	Hughes et al., 2004 [69]	Prospective case series	Royal Children’s Hospital	Australia	2000–2003
64	Bradley et al., 2004 [70]	Retrospective cohort study	Medical University of South Carolina	USA	2000–2003
65	Pizarro et al., 2003 [71]	Retrospective cohort study	Nemours Cardiac center Wilmington, the Polish American Hospital in Krakow	USA, Poland	2000–2002
66	Malec et al., 2003 [72]	Retrospective cohort study	Jagiellonian University	Poland	1998–2002
67	Mair et al., 2003 [73]	Retrospective case series	General Hospital Linz	Austria	1999–2002
68	Mahle et al., 2003 [74]	Retrospective cohort study	Emory University School of Medicine	USA	1999–2002
69	Graham et al., 2005 [75]	Retrospective cohort study	Medical University of South Carolina	USA	2000–2005
70	Azakie et al., 2004 [76]	Retrospective cohort study	San Francisco Children’s Hospital and Pediatric Cardiac Program	USA	2001–2003

RCT: randomized control trial; USA: United States of America; UK: United Kingdom.