Comparison of Alternative Peripheral and Transfemoral Approaches for Transcatheter Aortic Valve Replacement: A Meta-Analysis of Propensity-Matched Studies
Table 2
Comparison of outcomes between transfemoral and alternative peripheral access.
Outcomes
No. of studies
No. of patients (TF)
No. of patients (AP)
No. of events (TF)
No. of events (AP)
Odds ratio, M-H random, 95% CI
value
I2(%)
Mortality
7
6729
2275
219 (3.3)
100 (4.4)
0.69 [0.51, 0.94]
0.02
5
Stroke
7
6729
2275
128 (1.9)
80 (3.5)
0.60 [0.43, 0.84]
0.003
0
Vascular complications
6
6561
2219
578 (8.8)
65 (2.9)
1.22 [0.88, 1.68]
0.23
2
Pacemaker implantation
6
6689
2235
1079 (16.1)
396 (17.7)
1.04 [0.79, 1.37]
0.77
46
Bleeding
6
6561
2219
607 (9.3)
294 (13.2)
0.85 [0.71, 1.02]
0.08
0
Acute kidney injury
6
6287
2190
348 (5.5)
105 (4.8)
1.01 [0.59, 1.71]
0.98
62
Values are number, percentage (in parentheses) AP, alternative peripheral; CI, confidence interval; M-H, Mantel-Haenszel; TF, transfemoral.
