| | Variable | Total
N = 458 | No event
N = 397 | Event
N = 61 | value |
| | Follow-up period (months) | 14.4 (8.2–20.9) | 15.7 (10.1–21.5) | 1.1 (1.0–6.5) | <0.001 | | Age (years) | 61 ± 13 | 59 ± 12 | 61 ± 15 | 0.075 | | Sociodemographic factors | | Men (n, %) | 245 (53%) | 216 (54%) | 29 (48%) | <0.001 | | Elderly (>65 y, n, %) | 183 (39%) | 151 (38%) | 32 (52%) | 0.317 | | Lifestyle risk factors | | Current smoking (n, %) | 95 (21%) | 83 (21%) | 12 (20%) | 0.825 | | Current drinking (n, %) | 89 (19%) | 76 (19%) | 13 (21%) | 0.690 | | Current health status | | Overall overweight/obesity (n, %) | 193 (42%) | 169 (43%) | 24 (39%) | 0.635 | | Diabetes (n, %) | 47 (10%) | 35 (9%) | 12 (20%) | 0.009 | | Hypertension (n, %) | 145 (32%) | 121 (30%) | 24 (39%) | 0.168 | | Dyslipidemia (n, %) | 217 (47%) | 193 (49%) | 24 (39%) | 0.177 | | Coronary heart disease (n, %) | 74 (16%) | 61 (15%) | 13 (21%) | 0.240 | | Atrial fibrillation (n, %) | 138 (30%) | 126 (32%) | 12 (20%) | 0.056 | | Chronic kidney disease (n, %) | 157 (34%) | 131 (33%) | 26 (43%) | 0.140 | | Hepatic insufficiency (n, %) | 25 (5%) | 19 (5%) | 6 (10%) | 0.106 | | Metabolic risk factor | | BMI (kg/m2) | 23.5 ± 3.5 | 23.5 ± 3.6 | 23.5 ± 3.2 | 0.764 | | SBP (mmHg) | 128 (115–144) | 128 (115–143) | 131 (114–146) | 0.391 | | DBP (mmHg) | 76 (67–86) | 76 (67–87) | 74 (66–82) | 0.161 | | Hemoglobin (g/L) | 131 (119–141) | 133 (121–143) | 124 (106–134) | <0.001 | | WBC (10^9/L) | 6.2 (5.1–7.7) | 6.3 (5.0–7.7) | 6.2 (5.2–7.5) | 0.661 | | Total lymphocyte count (10^9) | 1.5 (1.3–1.9) | 1.6 (1.3–1.9) | 1.4 (1.2–1.8) | 0.047 | | RDW (%) | 13.2 (12.7–14.1) | 13.2 (12.7–14.0) | 13.6 (12.7–14.9) | 0.082 | | Platelet (10^9/L) | 201 (166–244) | 202 (167–247) | 192 (166–214) | 0.143 | | Albumin | 38.9 (36.4–41.1) | 39.1 (36.8–41.3) | 37.2 (33.5–39.4) | <0.001 | | Aspartate aminotransferase (U/L) | 23.5 (19.0–32.0) | 24.05 (19.0–31.0) | 22.5 (18.3–32.8) | 0.874 | | Urea nitrogen (mmol/L) | 6.3 (5.2–8.0) | 6.4 (5.2–8.0) | 6.1 (5.0–8.2) | 0.450 | | Uric acid (umol/L) | 380 (312–465) | 380 (316–465) | 372 (306–467) | 0.869 | | TC (mmol/L) | 4.6 (3.8–5.4) | 4.6 (3.9–5.4) | 4.2 (3.4–5.1) | 0.043 | | TG (mmol/L) | 1.3 (1.0–1.8) | 1.3 (0.9–1.8) | 1.3 (1.0–1.8) | 0.690 | | HDL-c (mmol/L) | 1.0 (0.8–1.3) | 1.0 (0.9–1.3) | 1.0 (0.7–1.2) | 0.032 | | LDL-c (mmol/L) | 2.5 (2.0–3.1) | 2.5 (2.0–3.1) | 2.4 (1.8–3.0) | 0.120 | | PNI | 46.8 (43.9–50.1) | 47 (44.6–50.4) | 44.3 (39.1–47.1) | <0.001 | | RAR | 0.33 (0.31–0.38) | 0.34 (0.31–0.38) | 0.37 (0.33–0.43) | <0.001 | | RPR | 0.07 (0.05–0.08) | 0.07 (0.05–0.08) | 0.07 (0.06–0.09) | <0.001 | | HRR | 10.00 (8.67–10.91) | 10.08 (8.87–10.98) | 9.02 (7.44–10.28) | 0.033 | | PLR | 126.33 (99.30–169.01) | 126.05 (98.04–169.08) | 127.91 (105.43–168.52) | <0.001 | | Echocardiography | | LVEF (%) | 63.1 (56.1–66.9) | 63.1 (56.1–66.9) | 62.7 (57.5–66.9) | 0.908 | | LVEDD (mm) | 56.0 (50.0–62.0) | 56.0 (50.0–62.0) | 55.0 (49.0–62.0) | 0.528 | | LAD (mm) | 49.0 (44.0–55.0) | 49.0 (45.0–56.0) | 47.0 (44.0–52.0) | 0.032 | | Type of the surgery | | | | 0.509 | | Valve repair | 226 (49.3%) | 193 (48.6%) | 33(54.1%) | | | Valve replacement | 232 (50.7%) | 204 (51.4%) | 28 (45.9%) | | | Type of the valve | | | | 0.394 | | Mitral valve | 225 (49.1%) | 191 (48.1%) | 34 (55.7%) | | | Tricuspid valve | 204 (44.5%) | 179 (45.1%) | 25 (41.0%) | | | Aortic valve | 29 (6.3%) | 27 (6.8%) | 2 (3.3%) | |
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BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; RDW, red cell distribution width; TC, total cholesterol; TG, triglycerides; HDL-c, high-density lipoprotein-cholesterol; LDL-c, low-density lipoprotein-cholesterol; RAR, RDW-to-albumin ratio; RPR, RDW-to-platelet ratio; HRR, hemoglobin-to-RDW ratio; PLR, platelet-to-lymphocyte ratio; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic diameter; LAD, left atrium diameter.
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