Research Article

Benefits of On-X Mitral Valve Replacement in Cases of Infective Endocarditis

Table 1

Pre-operative characteristics of the total patients and per study group.

TotalOn-X groupSJM group value
(n = 40)(n = 13)(n = 27)

Age (years)54.1 ± 13.249.6 ± 9.856.3 ± 14.20.0493
Sex, male24 (60.0)8 (61.5)16 (59.3)>0.9999
Medical history
 Hypertension11 (27.5)2 (15.4)9 (33.3)0.2859
 Dyslipidemia4 (10.0)1 (7.7)3 (11.1)>0.9999
 Diabetes mellitus2 (5.0)2 (15.4)0 (0.0)0.0891
 Renal dysfunction (Cr >1.5 mg/dL)1 (2.5)1 (7.7)0 (0.0)0.3250
 COPD0 (0.0)0 (0.0)0 (0.0)>0.9999
 Atrial fibrillation2 (5.0)1 (7.7)1 (3.7)>0.9999
 Previous cardiac surgery4 (10.0)2 (15.4)2 (7.4)0.5839
NYHA functional class
 I or II29 (72.5)8 (61.5)21 (77.8)0.4507
 III or IV9 (22.5)4 (30.8)5 (18.5)0.4371
Organism causing the IE
 Genus Streptococcus19 (47.5)9 (69.2)10 (37.0)0.0915
 Genus Staphylococcus7 (17.5)3 (23.1)4 (14.8)0.6622
Staphylococcus aureus7 (17.5)3 (23.1)4 (14.8)0.6622
 Genus Enterococcus0 (0.0)0 (0.0)0 (0.0)>0.9999
 Other0 (0.0)0 (0.0)0 (0.0)>0.9999
 Unidentified13 (32.5)1 (7.7)12 (44.4)0.0302
Status of the endocarditis
 Active38 (95.0)13 (100.0)25 (92.6)>0.9999
 Healed2 (5.0)0 (0.0)2 (7.4)>0.9999
Indication(s) for initial surgery
 Heart failure17 (42.5)5 (38.5)12 (44.4)>0.9999
 Uncontrolled sepsis8 (20.0)3 (23.1)5 (18.5)>0.9999
 Systemic embolic event17 (42.5)11 (84.6)6 (22.2)0.0004
 Mobile vegetation12 (30.0)7 (53.8)5 (18.5)0.0323
 Severe mitral regurgitation36 (90.0)11 (84.6)25 (92.6)0.5839
Time from diagnosis to procedure (days)11.0 ± 10.59.5 ± 9.87.1 ± 9.30.7827

Values are mean ± SD or n (%). COPD chronic obstructive pulmonary disease, Cr serum creatinine, IE infective endocarditis, NYHA New York heart association, SJM St. Jude Medical.