Research Article

The Influence of Preoperative Neurological Complications on Outcomes after Surgery for Infective Endocarditis

Table 3

Postoperative data and outcomes.

All patients (n = 438)No neurological complications preoperative (n = 349, 79.7%)Neurological complications preoperative (n = 89, 20.3%) value

AKI KDIGO stages3 (1; 3)3 (1; 3)3 (1; 3)0.686
 146 (38.0%)39 (38.6%)7 (35.0%)
 28 (6.6%)7 (6.9%)1 (5.0%)
 367 (55.4%)55 (54.5%)12 (60.0%)
24 h-drainage loss (ml)650 (350; 1166)600 (300; 1166)650 (363; 1250)0.090
Re-thoracotomy due to bleeding/tamponade52 (12.1%)42 (12.3%)10 (11.2%)0.781
24 h-number of packed red blood cells, unit2 (0–27)2 (0–27)2 (0–21)0.540
24 h-number of fresh frozen plasma, unit0 (0–29)0 (0–29)0 (0–10)0.958
24 h-number of platelets, unit0 (0–8)0 (0–8)0 (0–5)0.420
Reintubation51 (12.0%)39 (11.5%)12 (13.8%)0.557
Tracheotomy59 (14.1%)47 (14.2%)12 (14.1%)0.993
ICU time (d)3 (1; 7)3 (1; 7)3 (1; 7)0.331
Postoperative days10 (7; 16)10 (7; 16)8 (5; 16)0.034
Readmission to the intensive care unit35 (8.3%)27 (8.0%)8 (9.3%)0.693
Postoperative day of readmission10 (5; 16)9 (5; 15)14 (4; 17)0.851
Postoperative delirium68 (16.1%)58 (17.2%)10 (11.8%)0.226
Neurological deficit27 (6.4%)24 (7.1%)3 (3.6%)0.237
CPR23 (5.4%)21 (6.2%)2 (2.3%)0.190
Atrial fibrillation (postoperative new)18 (4.9%)16 (5.4%)2 (2.8%)0.544
Pacemaker patient new post-op51 (11.6%)39 (11.2%)12 (13.5%)0.544
Postoperative myocardial infarction5 (1.2%)4 (1.2%)1 (1.2%)1.000
Bronchopulmonary infection44 (10.2%)35 (10.2%)9 (10.3%)0.969
Sepsis56 (13.0%)44 (12.8%)12 (13.8%)0.804
Sternal wound infection10 (2.5%)8 (2.5%)2 (2.6%)1.000
Hospital mortality72 (16.5%)55 (15.9%)17 (19.1%)0.461
 Cardiac death11 (15.3%)9 (16.4%)2 (11.8%)1.000
 Cerebral death1 (1.4%)1 (1.8%)0 (0.0%)1.000
 Sepsis10 (13.9%)8 (14.5%)2 (11.8%)1.000
 MOF50 (69.4%)37 (67.3%)13 (76.5%)0.472
7 d-mortality52 (11.9%)40 (11.5%)12 (13.5%)0.599
30-day mortality76 (17.4%)55 (15.8%)21 (23.6%)0.081
Survival/FU-time (years)2.8 (0.1; 7.0)2.9 (0.2; 7.0)1.5 (0.1; 6.9)0.225

AKI, acute kidney injury; KDIGO, Kidney Disease: Improving Global Outcomes; ICU, intensive care unit; CPR, cardiopulmonary resuscitation; MOF, multiple organ failure.