Clinical Study
Comparison of Photopic Negative Response of Full-Field and Focal Electroretinograms in Detecting Glaucomatous Eyes
Table 3
Sensitivity and specificity of the PhNR/b-wave amplitude ratio to discriminate glaucomatous eyes.
| | Sensitivity (95%CI) | Specificity (95%CI) | Cut-off value |
| | Early | | | |
| | Full-field ERG | 23.8 (12.1–39.5) | 97.4 (86.5–99.6) | 0.19 | | Focal ERG | | | | | Center | 61.9 (45.6–76.4) | 97.6 (87.4–99.6) | 0.22 | | Sup/temp | 75.6 (59.7–87.6) | 97.6 (87.1–99.6) | 0.23 | | Inf/temp | 73.1 (57.1–85.3) | 95.2 (83.8–99.3) | 0.29 | | Combined | 97.6 (87.7–99.6) | 92.9 (87.7–99.6) | |
| | Intermediate | | | |
| | Full-field ERG | 40.7 (22.4–61.2) | 97.4 (86.5–99.6) | 0.20 | | Focal ERG | | | | | Center | 67.9 (47.7–84.1) | 97.6 (87.4–99.6) | 0.22 | | Sup/temp | 85.7 (67.3–95.9) | 97.6 (87.1–99.6) | 0.23 | | Inf/temp | 78.6 (59.0–91.7) | 95.2 (83.8–99.3) | 0.29 | | Combined | 96.4 (87.7–99.6) | 92.9 (87.7–99.6) | |
| | Advanced | | | |
| | Full-field ERG | 69.7 (51.3–84.4) | 97.4 (86.5–99.6) | 0.20 | | Focal ERG | | | | | Center | 70.6 (52.5–84.9) | 97.6 (87.4–99.6) | 0.22 | | Sup/temp | 90.9 (75.6–98.0) | 95.6 (87.1–99.6) | 0.23 | | Inf/temp | 90.9 (75.6–98.0) | 95.2 (83.8–99.3) | 0.29 | | Combined | 97.1 (87.7–99.6) | 92.9 (87.7–99.6) | |
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PhNR: photopic negative response; CI: confidence interval; sup/temp: superior/temporal; inf/temp: inferior/temporal.
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