Spectral domain-OCT scans document the natural evolution of BVMD. Firstly a thicker layer between the photoreceptors inner/outer segment interface and the underlying RPE (previtelliform stage). The material is subsequently deposited under the neurosensory retina (vitelliform stage) and is sometimes accompanied with a neurosensory detachment (pseudohypopyon stage) secondary to its reabsorption, with abnormalities of the RPE and subsequent thinning of all retinal layers (vitelliruptive and atrophic stage).
