The Effect of Hormone Replacement Therapy on Dry Eye Syndrome Evaluated with Schirmer Test and Break-Up Time

Table 2

Demographic data of the included studies.

Study	Age		Menopause duration (year)		Number of participants ()
	HRT group	Control group	HRT group	Control group	HRT group	Control group
Guaschino et al., 2003 [6]	60.0 ± 5.4	59.8 ± 5.5	At least one year	At least one year	40	40
Erdem et al., 2007 [14]	50.2 ± 4.8	50.0 ± 4.6	3.2 ± 22	3.0 ± 1.6	20	5
Affinito et al., 2003 [7]	53.7 ± 5.9	51.9 ± 4.7	4.1 ± 2.7	3.4 ± 2.1	25	25
Taner et al., 2004 [15]	49.4 ± 5.5	52.1 ± 4.7	4.3 ± 4.4	5.7 ± 4.1	25	16
Scuderi et al., 2012 [13]	No data	No data	At least one year	At least one year	33	33

HRT: hormone replacement therapy.