Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

Figure 3

(a) Morphological changes in zebrafish injected with control morpholinos (control-MO) (left) or Snrnp200-MO (right) at 4 days postfertilization (dpf). Snrnp200-MO injection would result in morphological changes like malformed brains, short trunks, cardiac edema, and curved body axis, comparing with control-MO injection. (b–g) Retinal frozen sections of uninjected zebrafish (b and e) () and zebrafish injected with control MO (c and f) () and with Snrnp200-MO (d and g) () were immunostained for rhodopsin (b–d) or zpr-1 (e–g).

(a)

(b)

(c)

(d)

(e)

(f)

(g)