Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population
Table 1
Associations of ocular symptoms with meibomian gland loss (MGL) in 182 eyes of healthy volunteers.
Parameters
MGL (%)
Abnormal meiboscore (stage ≥ 2)
Yes
No
OR (95% CI)#
#
Dryness
31.2 ± 11.6
28.9 ± 12.7
1.28 (0.66–2.496)
0.46
Foreign body sensation
32.7 ± 13.1
27.8 ± 11.0
2.5 (1.3–4.82)
0.006
Pain
32.0 ± 12.0
28.1 ± 12.1
1.79 (0.92–3.5)
0.09
Ocular fatigue
30.9 ± 11.4
27.9 ± 13.7
1.72 (0.84–3.55)
0.13
Blurred vision
31.3 ± 11.9
28.6 ± 12.4
1.43 (0.75–2.72)
0.27
Discharge
30.0 ± 10.3
29.9 ± 12.4
0.71 (0.23–2.22)
0.56
Epiphora
31.3 ± 12.4
27.6 ± 11.5
1.33 (0.66–2.62)
0.41
Symptoms’ presence
(i) On waking
28.8 ± 12.5
30.2 ± 12.2
0.47 (0.19–1.14)
0.09
(ii) At evening
31.9 ± 13.0
28.8 ± 11.7
1.65 (0.84–3.21)
0.14
(iii) During all day
28.4 ± 11.5
31.0 ± 12.6
0.84 (0.43–1.64)
0.61
Puffy eyelids on waking
33.3 ± 12.8
28.6 ± 11.8
2.42 (1.17–5.02)
0.02
Sticky sensation
29.2 ± 10.9
30.0 ± 12.4
0.62 (0.22–1.72)
0.35
History of chalazion or hordeolum
38.1 ± 10.8
29.0 ± 12.0
6.33 (2.08–19.26)
0.001
logistic regression model adjusted for age and sex with the specified parameter as the independent variable and abnormal meiboscore as dependent variable.
