The Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Anterior Segment

Figure 6

Immunohistochemistry of MMP-9 in the cornea at different time points. (A) On day 1, there was no expression of MMP-9 in the cornea, 400x; (B) on day 7, the expression of MMP-9 was observed in the epithelium (indicated by an arrow), 400x; (C) on day 15, the MMP-9 level peaked, primarily in the epithelium (indicated by an arrow) but also in the stroma, 400x; (D) on day 30, the expression of MMP-9 was reduced, with only a small amount in the epithelium and stroma (indicated by an arrow), 400x; (E) on day 60, MMP-9 showed low expression only in the epithelium (indicated by an arrow), 400x; (F) on day 90, there was no expression of MMP-9 in the epithelium or stoma, 400x; (G) no MMP-9 expression was observed in the epithelium or stoma in the control group, 400x. Scale bar = 100 μm.