Simultaneous Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Correlate Retinal Thickness Changes to Vascular Abnormalities in an In Vivo Mouse Model of Retinopathy of Prematurity

Figure 3

FA and SD-OCT at early, mid, late, and mature phases of retinal vascular development. (1A–C) represents P19 RA mice (early phase RVD); (2A–C) represents P19 OIR mice (early phase RVD); (3A–C) represents P24 RA mice (mid phase RVD); (4A–C) represents P24 OIR mice (mid phase RVD); (5A–C) represents P32 RA mice (late phase RVD); (6A–C) represents P32 OIR mice (late phase RVD); (7A–C) represents P47 RA mice (mature phase RVD); and (8A–C) represents P47 OIR mice (mature phase RVD). Note: SD-OCT refers to spectral domain optical coherence tomography; RVD refers to retinal vascular development. Numbering: 1 refers to P19, 2 refers to P24, 3 refers to P32, and 4 refers to P47. Lettering: A refers to FA image, B refers to SD-OCT image, and C refers to thickness color map.