Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma
Table 1
Demographics and ocular characteristics of normal subjects and normal-tension glaucoma patients.
Normal ()
Normal-tension glaucoma ()
value
Demographic characteristics
Gender (male/female)
14/11
13/15
0.586
Laterality (right/left)
19/6
15/13
0.151
Age (years)
49.3 ± 10.0
53.7 ± 12.2
0.130
Clinical characteristics
SBP (mmHg)
119.2 ± 12.1
117.4 ± 13.9
0.762
DBP (mmHg)
77.1 ± 9.1
72.8 ± 11.6
0.151
MBP (mmHg)
91.1 ± 9.4
87.6 ± 11.9
0.318
MOPP (mmHg)
46.2 ± 5.7
45.3 ± 7.2
0.838
Heart rate (beats/min)
73.3 ± 9.8
72.8 ± 11.4
0.843
Hypertension medications
0 (0%)
5 (17.9%)
<0.001
Topical glaucoma medications
0 (0%)
20 (71.4%)
<0.001
Prostaglandin analogues
—
18 (64.3%)
Beta-adrenoceptor antagonists
—
3 (10.7%)
Carbonic anhydrase inhibitors
—
2 (7.1%)
Aloha-1-antagonists
—
1 (3.6%)
Ocular characteristics
Spherical equivalent (D)
−1.5 ± 1.9
−2.7 ± 2.0
0.052
IOP (mmHg)
14.6 ± 2.0
13.1 ± 2.7
0.016
CCT (μm)
536.0 ± 24.8
525.3 ± 36.2
0.277
MD (dB)
−0.3 ± 1.5
−4.6 ± 4.2
<0.001
MD (1/Lambert)
1.0 ± 0.3
0.5 ± 0.4
<0.001
PSD (dB)
1.6 ± 0.5
7.6 ± 4.6
<0.001
PSD (1/Lambert)
1.5 ± 0.2
11.0 ± 15.7
<0.001
The data are given as mean ± SD. The difference between groups was analyzed using χ2 test. The difference between groups was determined using analysis of variance with the Mann–Whitney test. SBP: systolic blood pressure; DBP: diastolic blood pressure; MBP: mean blood pressure; MOPP: mean ocular perfusion pressure; IOP: intraocular pressure; CCT: central cornea thickness; MD: mean deviation; PSD: pattern standard deviation.
