Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma

Table 5

Comparison of parameters using the area under receiver operating characteristics curve and sensitivities at fixed specificities.

	Normal versus normal-tension glaucoma
	AUROC (SE)	Sn/Sp (Sp > 90%)
OCT-A whole image vessel density	0.950 (0.027)	82.14/92.00
OCT-A inside disc vessel density	0.931 (0.034)	78.57/92.00
OCT-A peripapillary vessel density	0.830 (0.056)	60.71/92.00
LSFG MBRA	0.793 (0.065)	60.71/92.00
LSFG MBRV	0.601 (0.079)	21.43/92.00
LSFG MBRT	0.601 (0.079)	28.57/92.00
GCC thickness	0.970 (0.021)	92.86/92.00
RNFL thickness	0.906 (0.039)	75.00/96.00

for comparison of OCT-A whole image vessel density. for comparison of OCT-A inside disc vessel density. for comparison of OCT-A peripapillary vessel density. AUROC: area under receiver operating characteristic curve; SE: standard error; OCT-A: optical coherence tomography angiography; LSFG: laser speckle flowgraphy; MBR: mean blur rate; MBR_A: mean MBR in all areas; MBR_V: mean MBR in the vessel area; MBR_T: mean MBR in the tissue area; GCC: ganglion cell complex; RNFL: retinal nerve fiber layer; Sn: sensitivity; Sp: specificities.