ATF4 Involvement in TLR4 and LOX-1-Induced Host Inflammatory Response to Aspergillus fumigatus Keratitis

Figure 2

ATF4 was increased in mice corneas of A. fumigatus keratitis developed by corneal epithelium scratch. (a) The significant corneal opacity of C57BL/6 mice models was developed by corneal epithelium scratch formed at 1 day after infection, which persisted up to 5 days. (b) After A. fumigatus infection, ATF4 protein expression was confirmed by western blot to be elevated in infected mouse corneas at 3 days after infection and completely degraded at 5 days. Mean values and standard deviations of two independent experiments are shown; .

(a)

(b)