Systematic Assessment of Clinical Methods to Diagnose and Monitor Diabetic Retinal Neuropathy

Table 2

Number of studies with electrophysiology investigations demonstrating evidence of change in pre- or early diabetic retinopathy.

Electrophysiology	Compelling	Moderate	Weak	No evidence despite investigation
Electrophysiology total	69	8	1	0
VEP	16	2	0	0
PERG	16	6	3	0
MfERG	27	2	0	0
Scotopic b-wave	10	1	0	1
Implicit times (ITs)	25	3	0	1
Oscillatory potentials (OPs)	23	5	1	1

MfERG, OPs, and ITs had the greatest volume of evidence of diabetic retinal damage and, along with scotopic b-waves, the greatest proportion of compelling or indicative evidence of all electrophysiological tests.