Neurodegeneration in Patients with Type 2 Diabetes Mellitus without Diabetic Retinopathy
Table 2
Structural measurements obtained with Spectralis OCT in healthy controls and patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy.
Peripapillary measurements
Healthy
DM2
Mean (±SD)
Mean (±SD)
RNFL Glaucoma
Average
102.30 (±9.22)
95.93 (±12.10)
0.002
Superior
123.42 (±16.58)
118.98 (±19.37)
0.180
Nasal
75.92 (±15.29)
72.48 (±14.84)
0.214
Inferior
135.50 (±17.01)
123.85 (±18.91)
0.001
Temporal
74.17 (±15.58)
68.22 (±9.73)
0.013
Superotemporal
137.27 (±16.77)
132.10 (±21.76)
0.148
Inferotemporal
149.85 (±21.17)
135.10 (±20.44)
<0.001
Superonasal
109.57 (±22.76)
105.85 (±22.89)
0.374
Inferonasal
121.15 (±24.61)
112.60 (±23.81)
0.055
RNFL Axonal Analytics
Average
103.69 (±9.55)
97.12 (±12.29)
0.001
Superior
125.63 (±17.02)
120.18 (±18.95)
0.102
Nasal
77.98 (±14.18)
74.27 (±15.38)
0.173
Inferior
136.97 (±17.41)
125.50 (±20.14)
0.001
Temporal
73.98 (±13.33)
68.42 (±10.96)
0.014
Superonasal
112.59 (±22.79)
107.53 (±21.35)
0.214
Inferonasal
123.68 (±23.26)
114.65 (±24.80)
0.043
Superotemporal
138.66 (±18.20)
132.82 (±22.22)
0.120
Inferotemporal
150.27 (±22.38)
136.35 (±21.08)
0.001
Papillomacular bundle
58.10 (±10.50)
53.27 (±8.31)
0.006
Nasal/temporal index
1.10 (±0.32)
1.11 (±0.29)
0.793
Bold letters indicate . Asterisks mark significant values according to Bonferroni corrections for multiple comparisons. DM2, type 2 diabetes mellitus; RNFL: retinal nerve fiber layer; SD, standard deviation.
