Research Article
Evaluation of Cerebrospinal Fluid Pressure by a Formula and Its Role in the Pathogenesis of Glaucoma
Table 1
Descriptive statistics for glaucomatous and nonglaucomatous patients.
| | | Glaucoma (n = 53) | Normal (n = 33) | Comparison test | | Mean | Standard deviation | Mean | Standard deviation | value |
| | Age (years) | 72.32 | 7.67 | 68.13 | 15.59 | <0.001 | | Systolic blood pressure (mmHg) | 124.91 | 15.24 | 130 | 16.22 | 0.986 | | Diastolic blood pressure (mmHg) | 71.32 | 9.10 | 71.88 | 9.81 | 0.425 | | Height (m) | 1.65 | 0.09 | 1.68 | 0.11 | 0.024 | | Weight (Kg) | 67.45 | 10.98 | 70.69 | 21.57 | 0.004 | | BMI (kg/m2) | 24.87 | 3.17 | 24.58 | 5.32 | 0.085 | | Heart rate (bpm) | 66.26 | 11.04 | 66.88 | 11.02 | 0.745 | | Visual acuity (10/10) | 9.4 | 1.43 | 8.12 | 2.29 | 0.001 | | Refractive error (diopters) | 1.22 | 1.81 | −3 | 5.196 | 0.001 | | IOP (mmHg) | 15.85 | 2.73 | 15.18 | 1.62 | 0.208 | | Anamnestic IOP (mmHg) | 21.04 | 5.71 | 15 | 1.97 | <0.001 | | CSFP (mmHg) | 7.43 | 2.06 | 8.14 | 4.52 | <0.001 | | Axial length (mm) | 23.68 | 1.58 | 24.09 | 1.99 | 0.542 | | Anterior chamber depth (mm) | 2.76 | 0.78 | 2.49 | 0.58 | 0.585 | | CCT (um) | 534.21 | 36.09 | 552.69 | 30.96 | 0.210 | | Superior RNFL thickness (um) | 83.06 | 13.29 | 94.75 | 6.05 | 0.001 | | Inferior RNFL thickness (um) | 79.83 | 13.97 | 91.63 | 7.68 | 0.013 | | Foveal thickness (um) | 253.11 | 29.06 | 272.69 | 30.15 | 0.862 | | MD (dB) | −3.59 | 4.72 | −0.47 | 0.72 | <0.001 | | PSD (dB) | 4.32 | 4.33 | 1.57 | 0.43 | <0.001 | | TLCPD (mmHg) | 8.42 | 3.27 | 7.51 | 3.47 | 0.235 | | Anamnestic TLCPD (mmHg) | 13.61 | 6.18 | 7.33 | 3.97 | <0.001 |
|
|
n = number of eye; BMI = body mass index; IOP = intraocular pressure; CSFP = cerebrospinal fluid pressure; CCT = central corneal thickness; RNFL = retinal nerve fiber layer; MD = mean deviation; PSD = pattern standard deviation; TLCPD = translamina cribrosa pressure difference.
|
