Effect of Ocular Hypertension on D-β-Aspartic Acid-Containing Proteins in the Retinas of Rats

Table 1

Identification of proteins.

Protein	Accession	Score	Coverage	Proteins	Unique peptide	Peptides	PSMs	Aas	MW	pI
Expressed proteins identified by LC-MSMS from rat retina with ocular hypertension (OH)
Alpha-enolase	P04764	473.34	90.32%	3	21	50	161	434	47.1	6.57
ATP synthase subunit beta	P10719	193.82	74.67%	6	20	31	63	529	56.3	5.34
S-arrestin	P15887	135.47	79.90%	2	16	30	50	403	44.9	6.06
Glial fibrillary acidic protein	P47819	131.38	76.74%	3	20	43	58	430	49.9	5.44
ATP synthase subunit alpha	P15999	118.77	55.15%	8	15	34	49	553	59.7	9.19
Vimentin	P31000	79.57	59.44%	2	9	29	35	466	53.7	5.12
Spliceosome RNA helicase Ddx39b	Q63413	52.87	42.99%	3	7	17	22	428	49	5.67
Heterogeneous nuclear ribonucleoprotein H	Q8VHV7	42.71	40.76%	1	2	15	19	449	49.2	6.06
Dynactin subunit 2	Q6AYH5	41.95	46.27%	1	7	13	14	402	44.1	5.26
Protein kinase C and casein kinase substrate in neurons protein 1	Q9Z0W5	40.49	50.57%	1	5	20	23	441	50.4	5.24
Glutamate dehydrogenase	P10860	37.86	39.07%	1	4	17	24	558	61.4	8
Fascin	P85845	35.51	39.55%	1	4	12	14	493	54.5	6.74
Heterogeneous nuclear ribonucleoprotein H2	Q6AY09	34.5	34.74%	1	2	14	17	449	49.3	6.3
Identified proteins in normal tension (NT)
Alpha-enolase	P04764	391.19	88.02%	3	19	46	140	434	47.1	6.57
ATP synthase subunit beta	P10719	177.21	71.27%	6	20	32	61	529	56.3	5.34
S-arrestin	P15887	131.58	73.95%	1	14	31	58	403	44.9	6.06
ATP synthase subunit alpha	P15999	119.11	56.78%	8	14	33	51	553	59.7	9.19
Vimentin	P31000	64.21	53.65%	3	8	26	30	466	53.7	5.12
Protein kinase C and casein kinase substrate in neurons protein 1	Q9Z0W5	63.5	56.92%	1	9	26	29	441	50.4	5.24
Glial fibrillary acidic protein	P47819	61.6	59.53%	1	9	26	29	430	49.9	5.44
Spliceosome RNA helicase Ddx39b	Q63413	52.12	51.40%	3	10	23	30	428	49	5.67
Dynactin subunit 2	Q6AYH5	48.74	52.49%	1	9	17	19	402	44.1	5.26
Glutamate dehydrogenase 1	P10860	40.67	35.13%	1	4	17	22	558	61.4	8
Heterogeneous nuclear ribonucleoprotein H	Q8VHV7	38.24	44.99%	3	5	16	21	449	49.2	6.06
4-Trimethylaminobutyraldehyde dehydrogenas	Q9JLJ3	33.23	36.64%	1	4	15	16	494	53.6	6.92

PSM: peptide sequence match; Aas: amino acids; MW: molecular weight (kDa).