Identification of a Heterozygous Mutation in the TGFBI Gene in a Hui-Chinese Family with Corneal Dystrophy

Figure 1

Pedigree of the Hui-Chinese family with GCD1 and sequencing analysis of TGFBI c.1663C > T mutation. (a) Pedigree of the GCD1 family. Squares and circles represent males and females, respectively. Solid symbols indicate patients, and open symbols indicate unaffected individuals. (b) The patient II : 1 with the heterozygous TGFBI c.1663C > T mutation. (c) The unaffected family member (I : 1) with the TGFBI c.1663C. GCD1, granular corneal dystrophy type I; TGFBI, transforming growth factor beta-induced gene.