Research Article

Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects

Table 1

Serum thyroid hormones: FT4 (pmol/L), FT3 (pmol/L), and TSH (mE/L) measured in different disease groups.

Disease groupFT4FT3TSH

1. Euthyroid without keratoconus (n = 83)1.20 ± 0.143.32 ± 0.421.50 ± 0.62
1.18; 0.223.30; 0.601.48; 0.83

2. Euthyroid with keratoconus (n = 375)1.20 ± 0.133.45 ± 0.451.64 ± 0.57
1.19; 0.213.4; 0.501.63; 0.85

3. Hypothyroid without keratoconus (n = 69)1.38 ± 0.273.11 ± 0.472.17 ± 1.74
1.36; 0.343.00; 0.70a1.67; 2.43

4. Hypothyroid with keratoconus (n = 86)1.29 ± 0.213.41 ± 0.462.72 ± 1.48
1.25; 0.243.40; 0.503.10; 2.20

Values represent the mean ± standard deviation or the median; interquartile range, as indicated. aFor this group, n = 65.