Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects

Table 3

Corneal tomographic parameters measured with the Pentacam in different disease groups.

Disease group	ISV	IVA	KI	CKI	IHA	IHD
1. Euthyroid without keratoconus (n = 82)	21.31 ± 10.98	0.18 ± 0.15	1.02 ± 0.03	1.07 ± 0.67	6.42 ± 5.59	0.02 ± 0.10
	18.00; 14.00	0.15; 0.14	1.03; 0.04	1.00; 0.01	5.20; 6.60	0.01; 0.01
2. Euthyroid with keratoconus (n = 374)	101.17 ± 50.28	1.07 ± 0.52	1.26 ± 0.18	1.06 ± 0.24	34.65 ± 57.29	0.13 ± 0.11
	93.00; 59.00	1.00; 0.72	1.23; 0.19	1.04; 0.09	24.40; 33.42	0.11; 0.09
3. Hypothyroid without keratoconus (n = 78)	16.20 ± 6.25	0.12 ± 0.07	1.02 ± 0.02	1.00 ± 0.007	4.92 ± 4.46	0.01 ± 0.009
	15.00; 7.00	0.11; 0.08	1.02; 0.02	1.00; 0.01	3.40; 5.85	0.008; 0.008
4. Hypothyroid with keratoconus (n = 90)	102.64 ± 61.11	1.00 ± 0.49	1.25 ± 0.17	1.06 ± 0.08	30.87 ± 29.2	0.12 ± 0.07
	94.00; 66.75	0.98; 0.65	1.23; 0.22	1.05; 0.08	23.60; 29.17	0.11; 0.10
Difference between groups:
1-2
3-4
1–3			—	—	—
2–4	—	—	—	—	—	—

Values represent the mean ± standard deviation or the median; interquartile range, as indicated. ; . ISV: index of surface variance; IVA: index of surface asymmetry; KI: keratoconus index; CKI: center keratoconus index; IHA: index of height asymmetry; IHD: index of height decentration.