Research Article

Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects

Table 4

Biomechanical parameters measured with the ocular response analyzer in different disease groups.

Disease groupKMICHCRF

1. Euthyroid without keratoconus (n = 78)0.71 ± 0.3910.00 ± 1.909.89 ± 1.95
0.67; 0.539.95; 2.629.55; 2.85

2. Euthyroid with keratoconus (n = 325)0.09 ± 0.408.15 ± 1.737.06 ± 2.08
0.06; 0.578.10; 2.206.90; 2.50

3. Hypothyroid without keratoconus (n = 72)0.81 ± 0.3210.28 ± 1.8810.00 ± 1.96
0.88; 0.429.95; 2.629.60; 2.80

4. Hypothyroid with keratoconus (n = 77)0.04 ± 0.418.18 ± 2.057.00 ± 2.46
0.02; 0.578.30; 2.557.10; 2.70

Difference between groups:
1-2
3-4
1–3
2–4

Values represent the mean ± standard deviation or the median; interquartile range, as indicated. ; . KMI: keratoconus match index; CH: corneal hysteresis; CRF: corneal resistance factor.