Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects

Table 5

Corneal endothelium evaluated with the EM-3000 specular microscope in different disease groups.

Disease group	Endothelial cell density	Central corneal thickness
1. Euthyroid without keratoconus	2606 ± 360	507.69 ± 99.49
	2690; 452	525.00; 60
	(n = 70)	(n = 65)
2. Euthyroid with keratoconus	2523 ± 362	451.44 ± 107.99
	2558; 421	474.00; 73
	(n = 302)	(n = 277)
3. Hypothyroid without keratoconus	2586 ± 387	512.26 ± 98.75
	2598; 401	528.00; 41
	(n = 68)	(n = 65)
4. Hypothyroid with keratoconus	2501 ± 382	459.36 ± 100.33
	2558; 381	479.00; 83
	(n = 62)	(n = 58)
Difference between groups
1-2
3-4	—
1–3	—	—
2–4	—	—

Values represent the mean ± standard deviation or the median; interquartile range, as indicated. ; .