PPARG Polymorphisms Are Associated with Unexplained Mild Vision Loss in Patients with Type 2 Diabetes Mellitus

Table 3

PPARG allele frequencies in the 135 residents with unexplained mild visual impairment (UMVI) and 133 residents with normal vision (NV).

SNP	Alleles	UMVI residents	NV residents	value	MAF	OR (95%CI)
		number (%)	number (%)
rs10865710	G	163 (60.4)	14 (5.3)	6.57E − 42	0.33	27.42 (15.18–49.51)
	C	107 (39.6)	252 (94.7)
rs1801282	G	22 (8.1)	0 (0)	1.99E − 06	0.04	NA
	C	248 (91.9)	266 (100)
rs709158	G	95 (58.6)	24 (21.4)	1.00E − 09	0.43	5.20 (3.00–9.00)
	A	67 (41.4)	88 (78.6)
rs3856806	T	88 (32.6)	21 (7.9)	1.22E − 12	0.20	5.64 (3.38–9.42)
	C	182 (67.4)	245 (92.1)

MAF = minor allele frequency; OR = odds ratio; CI = confidence interval; NA, the odds ratio was not available where the number of individuals with two copies of the risk allele was zero. χ² test.