Analysis of TGFBI Gene Mutations in Three Chinese Families with Corneal Dystrophy

Figure 1

The pedigree of the three families indicates a likely autosomal dominant inheritance of Reis–Bücklers corneal dystrophy over four generations (Family 1 and Family 2) and three generations (Family 3). The genotypes and disease onset (inside parentheses) are given below the pedigree symbols. Black filled and blank symbols represent affected and unaffected status, respectively.