Evaluation of Retinal Pigment Epithelial Cell Cytotoxicity of Recombinant Tissue Plasminogen Activator Using Human-Induced Pluripotent Stem Cells

Figure 1

Cytotoxicity of 1-hour rtPA exposure in RPE. Phase-contrast images of hfRPE (a), hiPSC-RPE ((b) 454E2), hiPSC-RPE ((c) 253G1), and ARPE19 (d). Scale bar, 200 mm. Cell damage rate of eight different dilutions in hfRPE (e), hiPSC-RPE ((f) 454E2), hiPSC-RPE ((g) 253G1), and ARPE19 (h); for each; .

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