In Vitro Study of Combined Application of Bevacizumab and 5-Fluorouracil or Bevacizumab and Mitomycin C to Inhibit Scar Formation in Glaucoma Filtration Surgery

Table 1

Human Tenon’s fibroblasts (HTFs) and human umbilical vein endothelial cells (HUVECs) were incubated with different concentrations of bevacizumab (BVZ), 5-fluorouracil (5-Fu), BVZ/5-Fu, mitomycin C (MMC), and BVZ/MMC for cytotoxicity analyses.

	Medicine and concentration (mg/ml)		Medicine and concentration (mg/ml)
HTF	BVZ	0.025
		0.25
		2.5
	5-Fu	0.05	BVZ 0.25/5-Fu	0.05
		0.5		0.5
		5		5
	MMC	0.00002	BVZ 0.25/MMC	0.00002
		0.0002		0.0002
		0.002		0.002
HUVEC	BVZ	0.025
		0.25
		2.5
	5-Fu	0.05	BVZ 2.5/5-Fu	0.05
		0.5		0.5
		5		5
	MMC	0.00002	BVZ 2.5/MMC	0.00002
		0.0002		0.0002
		0.002		0.002