Research Article

In Vitro Study of Combined Application of Bevacizumab and 5-Fluorouracil or Bevacizumab and Mitomycin C to Inhibit Scar Formation in Glaucoma Filtration Surgery

Table 3

Cell viability of human Tenon’s fibroblasts (HTFs) after treatment with bevacizumab (BVZ), 5-fluorouracil (5-Fu), BVZ/5-Fu, mitomycin C (MMC), and BVZ/MMC.

Medicine and concentration (mg/ml)Absorbance at 570 nm (ratio, compared to PBS)Medicine and concentration (mg/ml)Absorbance at 570 nm (ratio, compared to PBS)

BVZ0.0251.0596 ± 0.0307
0.250.7871 ± 0.1008
2.50.2376 ± 0.0084
5-Fu0.051.0161 ± 0.0335BVZ0.25/5-Fu0.050.6626 ± 0.1499
0.50.8961 ± 0.02840.50.7962 ± 0.0365
50.8417 ± 0.025850.7426 ± 0.0270
MMC0.000021.0994 ± 0.0461BVZ0.25/MMC0.000020.4837 ± 0.1337
0.00021.0390 ± 0.02500.00020.5255 ± 0.0942
0.0020.9512 ± 0.02660.0020.4980 ± 0.1015